The Jets face Patrick Mahomes without edge rusher Joseph Ossai and cornerback Nahshon Wright. Mahomes threw for 321 yards and 3 touchdowns at Denver last week.
Kansas City averages 134.1 rushing yards per game, fifth in the NFL. New York allows 123.6 per game, ranked 21st.
Over 47.5 also relies on New York carrying its recent big plays into this matchup. The Jets averaged 7.16 yards per play across their last two games, against Miami and Las Vegas.
AD Mitchell caught 7 passes for 142 yards and a touchdown against Las Vegas. He now faces a Chiefs secondary without cornerback Mansoor Delane.