Bryant committed 22 fouls and gave Siena 32 free-throw attempts in Monday's opener. Quinnipiac earned 24 attempts at Michigan State that same night.
Quinnipiac -5.5 is a bet on attacking that defense inside and adding second shots through Keith McKnight. He grabbed 80 offensive rebounds across 32 games last season, while Bryant allowed Siena 11 offensive rebounds on Monday.
McKnight made 132 of 234 two-point attempts last season. He played 25 minutes in the opener.