The Lakers head to Intuit Dome for their third game in four nights after allowing Portland 136 points Tuesday. The Clippers have had two days off.
Clippers +4.5 gives the rested home team room to stay close with the scoring it found in the first meeting. Darius Garland had 26 points against the Lakers on Oct. 23 and is projected to start again.
Brook Lopez added 22 off the bench that night. The Clippers' reserves outscored the Lakers' reserves 46-25.
The Clippers also scored 48 points in the paint and grabbed 11 offensive rebounds for 15 second-chance points against the Lakers.