Indiana has to defend Tyrese Maxey without T.J. McConnell or Ben Sheppard. Maxey averaged 28.8 points across Philadelphia's first 4 games.
I'm backing 76ers -4.5 with Joel Embiid projected to return after sitting Sunday. Indiana is missing its starting center, Ivica Zubac.
The Pacers took 53% of their shots in the paint in their first 3 games. That brings their offense toward Embiid, who helped Philadelphia's starting five hold the Knicks and Cavaliers to 56 points on 74 defensive possessions.
Philadelphia has two days off before this trip. Indiana gets one after playing Brooklyn on Sunday and Milwaukee on Monday.